Submit a consultation request and one of our patient care coordinators will get back to you soon about making an appointment that fits your schedule.

    By submitting this form, you will not be scheduled for an appointment, simply to let us know of your interest and to gather more information so we can efficiently assist you.


    Weight Loss Injections

    Weight Loss Injections with Semaglutide & Tirzepatide

    Achieve long-lasting weight loss

    If you have struggled to lose weight through diet and exercise or other weight loss methods, you are certainly not alone—over 40% of adults in the US are overweight. Thankfully, weekly semaglutide or tirzepatide injections have opened up a promising new possibility for men and women seeking weight management solutions.

    Complete your semaglutide weight loss transformation by adding Evolve’s non-surgical body sculpting technology which can help you tighten lax skin, boost fat removal, and tone underlying muscles.


    $1,200 for 12 weeks of treatment. See more details below.


    There is no required downtime after each injection.


    You may resume your normal activities after each treatment.


    Non-smokers, men and women 18+ years old in generally good health with a BMI over 30.

    What is semaglutide?

    Semaglutide is a medication that acts as an appetite suppressant; it resembles a natural hormone in our body called glucagon-like peptide 1 (GLP-1). This hormone helps control your blood sugar levels to help you lose weight and keep it off. Popular brands of semaglutide injection are Ozempic® and Wegovy™.

    How does semaglutide work for weight loss?

    Semaglutide works by mimicking GLP-1; it slows down the digestive process, boosts the release of insulin, and lowers the production of another hormone called glucagon to lower overall blood sugar levels. The end result can be significant, maintainable weight loss.

    What is tirzepatide?

    Tirzepatide is also a weight loss medication that combines the actions of GLP-1 peptides and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, both of which are hormones that regulate your metabolism. Tirzepatide is the active ingredient in Mounjaro®.

    How does tirzepatide work for weight loss?

    Activating both of these hormones improves glycemic control and promotes weight loss by enhancing insulin secretion, reducing glucagon secretion, slowing gastric emptying, and reducing appetite and food intake.

    What’s the difference between semaglutide and tirzepatide?

    By acting on both GLP-1 and GIP receptors, Tirzepatide helps control blood sugar more broadly, stimulates insulin release, reduces glucagon release, slows down food’s movement through the gut, and decreases appetite and food intake. Thus, Tirzepatide potentially offers a more comprehensive approach to managing blood sugar levels and body weight than targeting GLP-1 alone.

    Am I a good candidate for medical weight loss injections?

    Patients who have a BMI over 30 may benefit from semaglutide injections or tirzepatide injections. This weight management program may also benefit patients who have a BMI of 27 or greater who additionally have weight-related medical issues, such as high blood pressure, high cholesterol, or type 2 diabetes.

    Who should not use a semaglutide or tirzepatide medical weight management program?

    Weight loss injections may not benefit patients with certain conditions. If you have a personal or family history of medullary thyroid carcinoma or have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), you should not use semaglutide or tirzepatide.

    What are the benefits of semaglutide and tirzepatide?

    These weight loss injections can help patients lose weight safely and gradually and keep it off. Some of the other health benefits associated with semaglutide and tirzepatide weight loss injections include the following:

    • Lowers blood sugar, blood pressure, and inflammation
    • Suppresses appetite to help you feel full for longer and thus curb cravings
    • Enhances insulin synthesis and secretion
    • Lowers cardiovascular risk factors for conditions associated with obesity

    What is treatment like?

    During your consultation, we will assess your weight loss goals and body composition to determine if this treatment may help you safely achieve your weight loss goals.

    If we determine either semaglutide or tirzepatide injections are likely to positively support your medical weight loss journey, you can start treatment. Once your prescription comes in, you’ll come back to the office for a quick follow up to go over dosing and how to self inject at home, which is the most common choice for patients as it’s more convenient. However, coming in once weekly for to receive a quick injection of your specific dose at our office is also available. During your monthly, or as needed, body assessments, we will monitor your progress, answer any questions you may have, and otherwise coach you through the process.

    How many treatments are required to see results?

    The goal of each 12-week program is to lose 10% of your body weight, so depending on your goals, you may be satisfied after 1 treatment program or choose to complete multiple treatment programs.

    Although each medical weight loss clinic approaches medical weight loss in a different way, clinical research shows that 10% is the amount of weight you can lose and keep off with the combination of semaglutide or tirzepatide medications and accountability coaching.

    You may likely see your weight loss jump to more than 10% of your body weight, but we set the goal at 10% because it achieves significant improvements across all metabolic and inflammatory markers.

    Do the injections hurt?

    Most patients report that the weekly injections are relatively painless and easily tolerated. The thin needle is inserted just below the skin (subcutaneous), not into a vein or muscle. We will alternate the injection sites each week—under the skin of your stomach, thighs, or upper arm—to further minimize potential tenderness.

    Can I combine another treatment with weight loss injections?

    Yes! We recommend Evolve Tite & Tone to tighten lax skin, boost fat removal, and tone underlying muscles. One of the most popular non-surgical body contouring treatments, Evolve uses radiofrequency (RF) energy and EMS muscle stimulation to help your weight loss transformation look and feel more complete!

    We offer special pricing on Evolve for patients in our weight loss program: $1,500 for a package of 4 treatments (regularly $2,499 for package of 6 treatments)

    While combining non-surgical body treatments with semaglutide or tirzepatide can be beneficial, we do not recommend you take any other weight loss medication that is not a GLP-1 during your program unless otherwise directed by your primary physician.

    How much do weight loss injections cost in Joplin?

    Medical weight loss injections start at $1,200 for one 8-week (Tirzepatide) or 12-week (Semaglutide) treatment program. Pricing is subject to change.

    What is included in the cost of treatment?

    You’ll receive weekly semaglutide or tirzepatide injections and accountability coaching over the course of 12 weeks.

    Will I need to follow a strict diet to see results while getting weight loss injections?

    There is no specific diet or nutrition sessions required while having weight loss injections; that said, we recommend adopting a conscientious and sustainably flexible approach to nutrition to help you achieve optimal weight loss results as well as support your general health and wellness.

    • Choose healthier food options without becoming overly focused on restricting or counting calories.
    • Minimize the amount of fast-digesting carbs you consume (i.e., white bread, sugary desserts, potato chips or fries, sweet beverages).
    • Incorporate vegetables and ‘superfoods’ into your diet to be sure your nutritional needs are being met.

    Is semaglutide for weight loss safe?

    Yes, semaglutide has been in use since 2005. A 2022 meta-analysis reviewed the statistical data of eight randomized controlled trials. The study found that semaglutide achieved “significant body weight loss” and was deemed safe for overweight or obese individuals.

    What about tirzepatide?

    Yes, tirzepatide is also FDA-approved. A comprehensive safety study published in Frontiers in Endocrinology in 2023 reported that the safety profile of tirzepatide was similar to that of semaglutide. Regarding the efficacy of tirzepatide, a random, 36-week clinical trial showed that obese or overweight patients saw an average reduction of 20.9% of their total body weight.

    The most common side effects of semaglutide and tirzepatide include:

    Most common side effects of semaglutide include:

    • Nausea
    • Diarrhea
    • Vomiting
    • Constipation
    • Stomach pain
    • Headache
    • Fatigue
    • Digestive upset
    • Dizziness
    • Bloating
    • Belching
    • Gas
    • Heartburn

    These side effects are typically mild and are manageable by proper dosing and some overlap with the intended effect of “feeling full.”

    Tips for managing nausea from weight loss medications

    One of the most common side effects patients report when starting a medical appetite suppressant is nausea; we’ve compiled a list of tips to help manage this effect while you get used to the medication:

    • Slow down when eating, taking time between each bite and eating smaller portions
    • Eat foods that are high in water content (low sodium soup or sugar-free gelatin can be especially helpful)
    • Avoid lying down immediately after you eat
    • Go outdoors for fresh air
    • Do your injection in the evening before bed. Taking a Dramamine right before can also help alleviate nausea
    • Eat high-fiber foods the day of your injection
    • Avoid eating 2 hours before and after your injection
    Weight loss injections in Joplin, MO

    Semaglutide and tirzepatide weight loss injections are administered by Nurse Andrea under the direction of triple board-certified cosmetic surgeon Dr. Talon Maningas. Contact our Joplin or Northwest Arkansas office online or call (417) 437-0303 to schedule your consultation and start your weight-loss journey today.

    Had a great experience. Dr. Maningas and his staff are very kind. All of my questions were clearly answered and I felt completely comfortable.

    Patient Testimonial

    I cannot not say enough wonderful things about Dr. Maningas and his practice. Everyone is so pleasant. I could not be more happy with the care I received!

    Patient Testimonial

    Dr. Maningas is a fine person, skilled surgeon, and enjoys helping his patients. He will be a true asset to the community and I look forward to his return to Joplin.

    Frank Shagets, MD

    Request a Consultation

    Submit a consultation request and one of our patient care coordinators will get back to you soon

    about making an appointment that fits best with your schedule and surgical timeline.

      By submitting this form, you will not be scheduled for an appointment, simply to let us

      know of your interest and to gather more information so we can efficiently assist you.

      Is Semaglutide for weight loss safe?